Volumetric quantitative ablation margins for assessment of ablation completeness in thermal ablation of liver tumours
R.-M. Sandu et al.
Ensuring complete coverage of liver tumors with adequate margins during thermal ablation is essential for treatment success. Traditional 2D visual inspections are variable, so this study introduces a volumetric quantitative ablation margin (QAM) approach. Results confirmed its effectiveness, and the code is publicly available, promoting standardized, objective evaluation. Read more
Accuracy of electrode placement in ire treatment with navigated guidance
D. Stillström, R.-M. Sandu, and J. Freedman et al.
This study assesses the accuracy of electrode placement in irreversible electroporation (IRE) for liver tumors using a stereotactic CT-based navigation system. Analyzing data from 51 treatments involving 84 tumors in 60 patients, the study compared planned and actual electrode placements, measuring lateral and angular errors. The findings confirm that this navigation system is safe, accurate, and user-friendly for IRE treatments. Read more
Stereotactic image-guidance for ablation of malignant liver tumors
I. Paolucci, R.-M. Sandu, et al.
This book chapter in 'Liver Pathology' provides an in-depth review of stereotactic percutaneous ablation, a rapidly advancing treatment for liver tumors. Improved CT imaging and stereotactic image-guidance enhance the safety, efficacy, and accuracy of ablation, making it an increasingly favored option among physicians. Read more
Image-Guidance for Non-Anatomical Liver Resections: An ex-vivo Study
I. Paolucci, R.-M. Sandu, L.A. Sahli et al.
Non-anatomical resections of liver tumors are becoming ubiquitous because they spare a larger portion of healthy liver parenchyma. Image-guidance systems have been introduced to provide additional guidance, but are rarely used due to their inaccuracy. Therefore, we have designed a new navigation approach that renders a surgical plan intra-operatively in real time using only navigated ultrasound. Read more
Robotically customizable thermal ablation volumes
I. Paolucci, J.Hermann, R.-M. Sandu, et al.
Stereotactic percutaneous ablation is a fast advancing modality for treatment of tumors in soft solid organs such as the liver, kidney and lung. In this study, we have investigated the possibility of creating ablation volumes with configurable shapes through synchronous modulation of ablation power and applicator position, in an ex-vivo porcine liver model. Read more
Quantitative volumetric assessment of percutaneous image-guided microwave ablations for colorectal liver metastases
R.-M. Sandu, I. Paolucci, et al.
Quantitative volumetric assessment of ct-guided ablation treatments for colorectal liver metastases
R.-M. Sandu, I. Paolucci, et al.
Reference Values for Volumetric Capnography in Spontaneously Breathing Subjects
R.-M. Sandu
Capnography is a simple non-invasive technique for monitoring the CO2 concentration in the exhaled breath. It is used to detect early adverse respiratory events and life-threatening conditions by cardiologists, pediatrics, in respiratory therapy and emergency care. Although it describes the patient’s cardiorespiratory dynamics the technique is still underutilized due to a lack of quantitative means for assessing it. An automated analysis of the capnogram would allow a quantitative assessment of the cardiorespiratory states of both healthy and diseased patients. The typical feature values determined in this study for healthy subjects are comparable with values reported in related literature. Read more
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